Tropical sprue (TS) is a syndrome characterized by acute or chronic diarrhea, weight loss, and malabsorption of nutrients. It occurs in residents. Tropical Sprue; Kwashiorkor. Sprue, both tropical and nontropical, has been a subject of great interest to the medical community ever Sp: Esprue tropical. Tropical sprue is a chronic diarrheal disease, possibly of infectious origin, that involves the small intestine and is characterized by.

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Vitamin B 12 malabsorption may be noted in some people due to lack of pancreatic proteolytic activity and failure to cleave the R protein—vitamin B 12 complex. Bull World Health Organ 79 — Complete recovery is the rule in the returned traveller. Key references Nath SK.

Tropical malabsorption

Gastroenterology 58 — The mucosa of the small intestine of residents of the tropics is structurally different from that of residents of temperate countries. Your doctor may also use an enteroscopy to confirm your espeue. By using this site, you agree to the Terms of Use and Privacy Policy.

Protozoa are an important cause of traveller’s diarrhoea. Peroral capsule biopsy of the jejunal mucosa has been replaced by endoscopically obtained duodenal mucosal biopsy. Malabsorption is an important clinical problem both in visitors to the tropics and in native residents of tropical countries.


The histologic changes typically resemble that of gluten-sensitive enteropathy. The first description of tropical sprue. Khojasteh A, Haghighi P. The issue fropical whether this bacterial colonisation could lead to tropical sprue in those with a genetic predisposition has not been considered, especially as earlier studies predated current understanding on innate immune responses in the gastrointestinal tract.

Gut 24 — What Are the Symptoms tripical Tropical Sprue? A villous tip accentuation of intraepithelial lymphocytosis was not appreciable in most cases.

Am J Med 89 — Clin Microbiol Rev 5 — If you have tropical sprue, there may be signs of swelling in the lining of your small intestine. It usually does not recur in people who get it during travel to affected regions. Ann Intern Med — Role of bacterial toxins, bile acids, and free fatty acids in colonic water malabsorption in tropical sprue. Persistent diarrhea in the returning traveler: Common variable immunodeficiency occurs sporadically in residents of the tropics, and may present primarily as a malabsorption syndrome.

Infection with this protozoan is common in the tropics and is often a cause of diarrhoeal illness in visitors to the tropics. Abstract Malabsorption is an important clinical problem both in visitors to the tropics and in native residents of tropical countries.

J Gastroenterol Hepatol 18 — HLA and tropical espruue. The use of folic acid and vitamin B 12 in the treatment of tropical sprue was promoted in the late s by Dr. To help fight against this, she clarifies…. That’s why we love them.


A perspective on tropical sprue. Gut 5 45— Infect Immun 72 — In this study, 10 of 13 patients with sprue had aerobic bacteria in the small intestine in tropicl numbers median 3.

Clonal proliferation may occur secondary to chronic or recurrent infections of the intestine in esrue. The disease was first described by William Hillary in from the island of Barbados in the West Indies.

Tropical sprue – Wikipedia

It is of interest despite the essprue that it is unknown in many parts of the world and, even where endemic primarily India, Southeast Asia and the Caribbeanit affects relatively few of the population compared with the millions who suffer from parasitic and other tropical diseases. Stool cultures are rarely diagnostic in this setting but are performed in selected patients. The ileal mucosa displayed more severe villous blunting with higher Marsh stages than in the corresponding duodenum from 5 patients.

Protozoal infections of the small intestine are particularly common in tropical countries and may be associated with malabsorption.