Classics in Total Synthesis. By K.C. Nicolaou and E. J. Sorensen. Article (PDF Available) in Molecules 3(2) · February with 2, Reads. This book is essential for any synthetic organic chemist.[ ]. K. C. NICOLAOU, E. J. SORENSEN. CLASSICS IN. TOTAL. Page 2. Classics in Total Synthesis K. C. Nicolaou and. – E. J. Sorensen. VCH.

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One innovation is the introduction of a colored title page at the beginning of each chapter, presenting an attractive graphical illustration of the target structure, together with its natural source and a picture of the leader of the group that worked on the total synthesis. Chen received his A. Special emphasis is placed on the skillful use of graphics and schemes: Reaction sequences and synthetically crucial steps are presented in blue boxed sections.

However, the opportunity to similarly illustrate other parts of the chapter has not been taken; especially in the introduction, figures or graphics in color might have improved the accessibility of the contents.

The concept of the preceding volumes has been closely retained. And due to the excellent presentation of reaction mechanisms and very good explanations of selected reactions, it is a beautiful teaching material for the advanced student, in order to deepen the knowledge acquired in the study.

Didactically skillful approach, reflecting the world-wide standard way of teaching organic synthesis introduction, retrosynthetic analysis, synthesis.

Classics in Total Synthesis III

Classics in Total Synthesis III will surely itself become a classic in the literature on the state of the art of claasics organic synthetic tptal.


About the Author K. The very instructive concept of discussing and comparing several different syntheses of a target structure in a parallel fashion, which was introduced in the second volume of this series, on now been further developed in a clever way. You are currently using the site but have requested a page in the site. With didactic skill and clarity, K. Nicolaou has made outstanding contributions in his research field.

Nicolaou compiles in this textbook the important synthetic methods that lead to a complex molecule with valuable properties. About the Author K. Retaining his excellent, proven approach, world-famous chemist and passionate teacher K. He is the recipient of many prizes, awards and honors. Site Search ttotal all words. The present volume – and hopefully future books of this series – offer an exciting and outstanding overview of the subject of natural products total syntheses in its complexity and variety.

Nicolaou has earned three prestigious international honors recently, including the Nemitsas Prize in Chemistry. This book is a must for every synthetic chemist.

Nicolaou compiles and contrasts the important synthet. Important reactions are additionally deepened. Nicolaou has earned three prestigious international honors recently, including the Nemitsas Prize in Chemistry.

Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists.

Added to Your Shopping Cart. The main author Nicolaou is a top-notch US chemist, who is now regarded as the world’s leading synthetic chemist. This clearly demonstrates the increasing scientific, but also industrial, importance of complex syntheses of natural products.

Wiley-VCH – Classics in Total Synthesis III

Important formulas are, in addition, depicted in the margin, next to the passage syntehsis they are mentioned in the text. His impact on chemistry flows from his works in chemical synthesis and chemical biology described in over publications and 55 patents.


Nicolaou compiles and contrasts the important synthetic methods that lead to a complex molecule with valuable properties. Every synthetic organic chemist will want to have a copy on his or her desk. The book includes the years to and is for this reason, both, a kind syntthesis historical book and a reference book. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically.

The review of asymmetric halogenation reactions Chapter He is the recipient of many prizes, awards and honors. Further Targets, Strategies, Methods K. But of that multitude, only a few books have been as outstanding in recent years as the series Classics in Total Synthesis, written by K. Also particularly valuable for the reader are the short reviews nicolaoj specific topics, which have the scope and style of review articles.

Similar to its predecessors and completing the trilogy, this textbook analyzes the syntheses in a didactic manner, with several chapters including mini-reviews of key methodologies, and an emphasis on the history, mechanism, scope, and generality of the reactions.

Classics in Total Synthesis III: Further Targets, Strategies, Methods

A wonderful tool for learning and teaching and a must-have for all future and present organic and biochemists. Using his didactically skillful approach, K. In 26 chapters, including an introductory chapter, syntheses of more than 40 natural products or natural product core structures are discussed in detail.