Caesalpinia sappan L. (Leguminosae) is found in India, Malaysia, southern China, and tropical Asia, and its heartwood Sappan lignum is used as a red dye. Family Name: Fabaceae (Leguminosae). Common Names: Sappan Wood, Brazilwood Tree, Sappan. Chinese Name: 苏木. by; G. Renu, Sanjana Julias Thilakar, D. Narasimhan, Centre for Floristic Research, Department of Botany, Madras Christian College, Tambaram. (0 ratings).

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Conclusions We found that brazilin prepared from ethyl acetate extracts of C.

CIA has been widely used as the animal model in RA research and demonstrated to resemble p RA more closely in terms of clinical, histological and immunological features, as well as genetic linkage, compared with other experimental arthritis models [ 39 ]. Sappanwood may have even better prospects as a medicinal plant, and will go on being valued for its beautiful wood in cabinet-making as well as a source of fuelwood with high energy value.

BMD volumes in CIA-induced control group were significantly lower, compared to test volumes, in the left tibial metaphysis, the distal part of the calcaneous, and the distal part of the metatarsal bone, but did not improve after administration of Caesalpiia or brazilin. The order Meliolales comprises two families, namely, Armatellaceae and Meliolaceae.

Retrieved Jul 6, Dictionary of Economic Plants. Uses and Management Uses and Management Uses. Received Nov 15; Accepted Apr User Group specific search options Title. Caesalpinia sappan Caesalpinia sappan, Biancaea sappan x – 78k – jpg toptropicals.


Caesalpinia sappan caesalpinia sappan 01 jmpg. Brazilin selectively disrupts proximal IL-1 receptor signalling complex formation by targeting an IKK-upstream signalling components. Sp was lower in the normal group than in the groups in which CIA was induced. It prefers clay and limestone lands. Planta Medica 64 5: Nomenclature and Classification Nomenclature caesaloinia Classification.

Accumulations of DNA strand break and methotrexate cytotoxicity. Adjuvant arthritis in the rat.

Flowering can occur after one year of growth. Caesalpinia sappanRheumatoid arthritis, Collagen-induced arthritis, Brazilin, Pro-inflammatory cytokines. Cutting takes place every six years.

Caesalpinia sappan L. | Species | India Biodiversity Portal

Then the decoction is leaved for fermentation during several days according to the color expected to obtain. Antioxidant activity of Caesalpinia sappan heartwood. Dyeing of papers is performed in two ways: Use of sappan wood zappan the Far East is probably caesalpniia archaeological remains silk textiles from the Loulan site attest its use in the 2nd century BC.

MTX not only reduces pain and swelling in the joints, but also its damage and long-term disability.

Some reports have documented the synthesis of novel cytokines including IL, IL, and RANK ligand in the synovium, which secretes enzymes degrading proteoglycans and collagen, in turn causing bone loss [ 45 ].


It does not tolerate too wet soil conditions. User specific search options User.

Caesalpinia sappan L.

Extract of the dried heartwood of Caesalpinia sappan L. Background Rheumatoid arthritis RA is a systemic inflammatory disease of the synovium, cartilage, and bone.

Caesalpinia sappan Caesalpinia sappan, Biancaea sappan x – 69k – jpg toptropicals. You can help Wikipedia by expanding it.

Caesalpinia sappan L.

Caesalpinia sappan caesalpinia sappan x – k – jpg www. Fraction with retention times of about 7.

Wood is cut into small pieces so that brasilin oxidizes with air contact and to allow good extraction of the dye. From Wikipedia, the free encyclopedia.

The effective ingredient in fraction C was confirmed to be brazilin.

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Clinical scoring of arthritis CIA mice were evaluated by two independent observers three-to-four times in a week, with regards to the extent of all the inflammation, erythema, edema of the periarticular tissues, and enlargement, distortion, or ankylosis of the joints.

The main dye component in the heartwood of Caesalpinia sappan is brazilin, also present in brazilwood Caesalpinia echinata Lam. BBP wrote the paper and analyzed the data.