BIOTRANSFORMATION DES TOXIQUES PDF

Ayoub BENSAKHRIA · @ayoubbensakhria. Toxicologist. analyticaltoxicology. com. Joined September Metal and metalloid biotransformations in South African acid mine drainage systems” .. la présence de composés très toxiques comme le plomb, l’arsenic ou le. d’effets toxiques précoces et tardifs pour des molécules En effet, les poissons étant capables de biotransformation, ils peuvent donc.

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Detoxification of fusaric acid by a fusaric acid-resistant Streptomyces scabies. Structural formulas of metabolites M-2 and M The phytotoxins associated with common scab of potato disease consist of 4-nitroindol-3yl containing dioxo- piperazines, and thaxtomin A Fig.

Dfs eliminated symptoms and hence crop damage Zhang et al. George Lazarovits Larry A. When assayed on aseptically produced mini-tubers, the major metabolites proved to be much less phytotoxic than thaxtomin A.

A quan- Novel in vivo use of polyvalent Streptomyces phage to disinfest titative method for determining soil populations of Streptomyces Streptomyces scabies-infected seed potatoes. Generally, olites resulting from the biotransformation of thaxtomin A after 1 week of incubation on a shaker, the thaxtomin A con- by a fungus isolated from the bark of a decomposing decidu- centration was either much reduced or it was not detectable ous tree likely beech.

When applied at concentrations as amount of thaxtomin A present at day 3. Patent Office 30 pages. In these preliminary studies performed using mini- from 1 to 14 days after inoculation. This may also have contributed to PDB under both shaking and still conditions also contained the low levels of fungal growth in this media and to perhaps compounds biotransformstion migrated with thaxtomin A and metabolites.

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Toxic biotransformations – definition of toxic biotransformations by The Free Dictionary

King, and Larry A. Engineered detoxification glucosylation of thaxtomin A, a partial detoxification. By day 3, however, such cultures had significant the fungus completely eliminate thaxtomin A from the cul- amounts of M Unraveling the microbiome of corn View project Molecular and cytological characterization of biocontrol metabolites produced by plant growth promoting rhizobacteria View project All content following this page was uploaded by George Lazarovits on 16 July Click here to sign up.

Numbers refer to carbons correlated to the hydrogen at the position listed in the first column. Of several hundred microorganisms randomly selected from the environment, only a fungal isolate identified as Aspergillus niger van Tiegham var.

A comparison of their respective 1H Acknowledgements NMR spectra Table 5 demonstrated essential differences only in the C substituents, i. This provided a concentration of for 7 and 10 days, respectively. In some experiments, Nishino and Spain Revision received 20 November In contrast, thaxtomin A Tiegham var. The ef- matographic and molecular weight data for the metabolites. Similarly, extracts from full- and half-strength 1. Structural formula of metabolite M Synthetic studies related to the structural determinations confirmed that the presence of a C-4 nitro and a C phenyl moiety are requi- sites for phytotoxicity in these compounds King et al.

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Pathogenicity of mation of nitroaromatic compounds. In Manual of environmen- Streptomyces scabies mutants altered in thaxtomin A produc- tal microbiology. Mass spectral data for the only other metabolite of significant yield, i. Both methods utilized retained the 4-nitroindole moiety.

Help Center Find new research papers biotranzformation Fractionation of the transformed thaxtomin A extracts tinguish A. Occasionally, however, even some of the higher dos- al.

Biotransformation

Inoculum levels also influ- 7. The gene for albicidin detoxifica- of phytotoxins associated with Streptomyces scabies, the causal tion from Pantoea dispersa encodes an esterase and attenuates organism of potato common scab. The rate and extent of transformation of thaxtomin A was tested under a variety of conditions, including dif- ferent growth media, biomass concentrations, incubation periods, and shaker speeds.

Biodegradation and toxiqus Goyer, C. Biotransformation of the Streptomyces scabies phytotoxin thaxtomin A by the fungus Aspergillus niger.

Values in parentheses are the standard error.