The diagnostic assessment comprises laboratory testing (erythrocyte sedimentation The earlier term “arteritis temporalis,” once often used as a synonym, was .. Once steroid therapy has been started, the signs of mural inflammation visible. ABSTRACT – Giant cell arteritis (GCA) or temporal arteritis. (TA) with tions and relapse. KEY WORDS: diagnosis, giant cell arteritis, steroid therapy, treatment a prompt diagnostic, management and referral process for. GCA. • appropriate. Bei zu spät gestellter Diagnose und bei zu spätem Beginn der Kortikosteroidbehandlung besteht die große Gefahr einer beidseitigen Erblindung [7,19]. Es sollte.

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Diagnosis and treatment of giant cell arteritis.

Highly dosed corticosteroid therapy should always be indicated when suspicious clinical symptoms are present, even without any dramatic laboratory parameter changes.

In oktober werd de standaard becommentarieerd en geautoriseerd door de NHG-Autorisatiecommissie.

The Diagnosis and Treatment of Giant Cell Arteritis

When ASA is given in combination with corticosteroids, a proton pump inhibitor should also be given to prevent gastric ulcers. Existing data do not allow the efficacy of biologicals in GCA to be evaluated. Op geleide van klachten zeer geleidelijke vermindering van de dosering. Meijman, huisarts te Amsterdam; P. Proposal of an international consensus conference. Disease-modifying drugs particularly methotrexate have a corticosteroid sparing effect in GCA. Noltorp S, Svensson B: The diagnosis and treatment of giant cell arteritis.

Azathioprine offers an alternative to methotrexate treatment in patients with contraindications or who do not tolerate methotrexate 8 arteriiyis, e The American College of Rheumatology criteria for the classification of giant cell arteritis. Arteeiitis startdosering en snelle dosisvermindering werd ook in een ander cohortonderzoek aangemerkt als risicofactor voor terugval [Maradit Kremers ].


Verder kunnen klachten ontstaan door een verhoogd calciumgehalte [Van der Meer ]. Diagnosis shoud be confirmed by biopsy or sonography but diagnostic procedures shoud not delay therapy.

Diagnose und Therapie der Riesenzellarteriitis

What is the typical biopsy finding when a suspected diagnosis of giant cell arteritis is confirmed? Afhankelijk van de bevindingen bij de anamnese en het lichamelijk onderzoek kan een uitgebreider lichamelijk onderzoek, gericht op andere oorzaken, noodzakelijk zijn.

What is the dagnostik approach to diagnosing large-vessel vasculitis? Sluit veel voorkomende aandoeningen, die zich op ongeveer dezelfde wijze kunnen presenteren als PMR, uit voordat de diagnose PMR wordt gesteld:. The frontal branch of the superficial temporal artery shows bilateral signs of wall inflammation thickening, uptake of contrast agent solid arrow.

Polymyalgia rheumatica en arteriitis temporalis.

De negatieve LR was voor alle vragen niet onderscheidend. Clinical and serological findings of giant-cell arteritis.

Die Biopsie erfolgt einseitig. Magnetic resonance imaging depicts mural inflammation of the temporal artery in giant cell arteritis. Alendronate ttherapie the prevention and treatment of glucocorticoid-induced osteoporosis.

Two to six times more women are affected than men. Relapse in a population based cohort of patients with polymyalgia rheumatica.

The technique is high resolution 0. Signs of systemic inflammation The systemic inflammatory reaction is accompanied by a number of non-specific symptoms such as exhaustion, fever, night sweats, and weight loss. In de literatuur bestaat geen eenduidigheid over de mate van dosisaanpassing bij ziekte. Na zes maanden werd getracht de prednison af te bouwen.


Giant cell arteritis can cause diagnostic difficulties due to its heterogeneous symptomatology. Utility of erythrocyte sedimentation rate and C-reactive protein for the diagnosis of giant cell arteritis.

Myalgic syndrome with constitutional dignostik polymyalgia rheumatica. Visual prognosis in giant cell arteritis. Clin Exp Rheumatol ; 5: A year epidemiological, clinical and prognostic study. Prednisone plus methotrexate for polymyalgia rheumatica: A transducer of at least 9 MHz is required. Color-coded duplex sonography allows the temporal artery, extracranial vessels, and also the occipital, subclavian, and other arteries to be visualized noninvasively and examined for signs of inflammation.

Am J Med ; Swallowing claudication and pain in the tongue can also occur. Familial diagnostii is known. Die Therapieeinleitung erfolgt mit dem Stellen der klinischen Diagnose. Results The typical symptoms of new-onset GCA are bitemporal arteriitls, jaw claudiacation, scalp tenderness, visual disturbances, systemic symptoms such as fever and weight loss, and polymyalgia.

It manifests in diagnositk over the age of 50 years and is associated in about half of the thegapie with polymyalgia rheumatica PMR. Leeb en Bird hebben een scoresysteem ontwikkeld om de activiteit van PMR vast te kunnen stellen [Leeb ].