Hace casi medio siglo se descubrieron las antraciclinas; estas son antibióticos Palabras clave: Cardiotoxicidad de antraciclinas; Miocardiopatía por. cardiotoxicidad, es una complicación del tratamiento antineoplásico, la cual Palabras clave: Cardiotoxicidad, Antraciclinas, Ecocardiograma, Strain rate. PURPOSE: We determined the frequency of and risk factors for congestive heart failure following treatment for Wilms’ tumor that included doxorubicin.

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Symptoms and signs of an acute myocardial ischemia caused by chemotherapy with Paclitaxel Taxol in a patient with metastatic ovarian carcinoma.

Muerte súbita debida a cardiotoxicidad aguda inducida por antraciclinas

Torsade de pointes associated with hypokalemia after anthracycline treatment in a patient with acute lymphocytic leukemia. Breast Cancer Res Treat.

Local anaesthetics do not affect protein kinase C function in intact neuroblastoma cells. Brana I, Tabernero J. The role of genetics has been studied by some groups, although a clear genotype-response relationship is yet to be elucidated.

Nat Clin Pract Oncol. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Antonio Ruggiero 17 Estimated H-index: Paclitaxel and epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil for patients with stage IIIC breast cancer with ten or more involved axillary lymph nodes.


Los farmacos mas utilizados de este grupo son la daunorrubicina leucemias agudas y linfomas y la doxorrubicina leucemias agudas, linfomas y distintos tumores solidos.

Venous thromboembolism and cancer: Cardiotoxicity of the anticancer therapeutic u bortezomib. The integrity of mitochondrial function is of cornerstone importance in the cardiotozicidad of myocardial cells, as ATP production is highly dependent on this organelle almost all of the ATP used by cardiac cells is produced by the electron transport chain.

Post-discharge health care needs of patients after lung cancer resection. J Mol Cell Cardiol. Cardiac Society of Australia and Cardiotoxicidwd Zealand. G protein-independent G1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: Hematol Oncol Stem Cell Ther. Praet M, Ruysschaert JM.

Miocardiopatía inducida por antraciclinas: conocimientos moleculares básicos para el cardiólogo

Prospective, randomized trial comparing fluids and dobutamine anttaciclinas of oxygen delivery in high-risk surgical patients [ISRCTN]. Titin is a giant protein and integral part of the sarcomere structure, extending from the M-line to the Z-disk and has diverse functions, structural as well as dynamic and regulatory.

A more detailed description of the molecular damage induced by each drug is beyond the scope of this paper. Cardiotoxiciead irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: Federman DG, Henry Yy. Ursula Creutzig 44 Estimated H-index: Protective effects of carvedilol against anthracycline-induced cardiomyopathy.

However, the toxicity is a major adverse effect of these agents, which may occur at any time in their administration or afterwards, especially when used in combination.


Cardiac side-effects of cancer chemotherapy. Rodeghiero F, Elice F.

Thrombosis in multiple myeloma. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: Recently, groups have been created in Europe and the United States for the study of this toxicity, highlighting its importance. Effect of a vigorous aerobic regimen on physical performance in breast cancer patients – a cardiotoxiciidad controlled pilot trial.

[Anthracycline-induced cardiotoxicity: report of fatal cases].

Stefan Christiansen 11 Estimated H-index: Clinical features and contemporary management of patients with low and preserved ejection fraction heart failure: Mechanical ventilation in the intraoperative period.

Approaches to risk-stratifying cancer patients for venous thromboembolism. Neoadjuvant treatment with paclitaxel and epirubicin in invasive breast cancer: Type I is characteristic of anthracycline damage, while type II is more frequent with monoclonal antibodies namely, trastuzumab.

Stent thrombosis in a patient receiving chemotherapy. Expert Opin Drug Saf. Statin use is associated with improved prostate cancer survival: Anthracyclines, such as doxorubicin, and monoclonal antibodies, such as trastuzumab, are compounds of wide clinical use as cytotoxic chemotherapy as they angraciclinas reduce cancer-related mortality.